全文获取类型
收费全文 | 2330804篇 |
免费 | 174944篇 |
国内免费 | 3274篇 |
专业分类
耳鼻咽喉 | 32036篇 |
儿科学 | 75703篇 |
妇产科学 | 62693篇 |
基础医学 | 345324篇 |
口腔科学 | 63579篇 |
临床医学 | 209749篇 |
内科学 | 452540篇 |
皮肤病学 | 51688篇 |
神经病学 | 183771篇 |
特种医学 | 87902篇 |
外国民族医学 | 489篇 |
外科学 | 352840篇 |
综合类 | 47298篇 |
现状与发展 | 12篇 |
一般理论 | 848篇 |
预防医学 | 181134篇 |
眼科学 | 54128篇 |
药学 | 174540篇 |
9篇 | |
中国医学 | 4408篇 |
肿瘤学 | 128331篇 |
出版年
2019年 | 19553篇 |
2018年 | 27068篇 |
2017年 | 20368篇 |
2016年 | 22763篇 |
2015年 | 25661篇 |
2014年 | 36130篇 |
2013年 | 53988篇 |
2012年 | 74744篇 |
2011年 | 79467篇 |
2010年 | 47080篇 |
2009年 | 44604篇 |
2008年 | 74651篇 |
2007年 | 79543篇 |
2006年 | 80342篇 |
2005年 | 77822篇 |
2004年 | 74434篇 |
2003年 | 71631篇 |
2002年 | 69237篇 |
2001年 | 108539篇 |
2000年 | 111138篇 |
1999年 | 92849篇 |
1998年 | 25351篇 |
1997年 | 21970篇 |
1996年 | 22359篇 |
1995年 | 22563篇 |
1994年 | 20771篇 |
1993年 | 19598篇 |
1992年 | 71877篇 |
1991年 | 70046篇 |
1990年 | 68348篇 |
1989年 | 65626篇 |
1988年 | 60250篇 |
1987年 | 59079篇 |
1986年 | 55184篇 |
1985年 | 52965篇 |
1984年 | 39238篇 |
1983年 | 33303篇 |
1982年 | 19761篇 |
1981年 | 17770篇 |
1979年 | 35783篇 |
1978年 | 25578篇 |
1977年 | 21129篇 |
1976年 | 20254篇 |
1975年 | 21752篇 |
1974年 | 26090篇 |
1973年 | 24764篇 |
1972年 | 23179篇 |
1971年 | 22013篇 |
1970年 | 20221篇 |
1969年 | 19286篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
101.
R. García-Ramos D. Santos-García A. Alonso-Cánovas M. Álvarez-Sauco B. Ares A. Ávila N. Caballol F. Carrillo F. Escamilla Sevilla E. Freire J.C. Gómez Esteban I. Legarda L. López Manzanares E. López Valdés I. Martínez-Torres M. Mata I. Pareés B. Pascual-Sedano J.C. Martínez Castrillo 《Neurología (Barcelona, Spain)》2021,36(2):149-158
IntroductionThe main challenge of Parkinson's disease in women of childbearing age is managing symptoms and drugs during pregnancy and breastfeeding. The increase in the age at which women are having children makes it likely that these pregnancies will become more common in future.ObjectivesThis study aims to define the clinical characteristics of women of childbearing age with Parkinson's disease and the factors affecting their lives, and to establish a series of guidelines for managing pregnancy in these patients.ResultsThis consensus document was developed through an exhaustive literature search and a discussion of the available evidence by a group of movement disorder experts from the Spanish Society of Neurology.ConclusionsParkinson's disease affects all aspects of sexual and reproductive health in women of childbearing age. Pregnancy should be well planned to minimise teratogenic risk. A multidisciplinary approach should be adopted in the management of these patients in order to take all relevant considerations into account. 相似文献
102.
103.
104.
Andreas Glenthj Lasse H. Jakobsen Henrik Sengelv Syed A. Ahmad Kristian Qvist Annika Rewes Christian B. Poulsen Ulrik M. Overgaard Ingolf Mlle Marianne T. Severinsen Casper N. Strandholdt Jack Maibom Annette R. Kodahl Jesper Ryg Pernille Ravn Isik S. Johansen Sren N. Hels Sren Jensen‐Fangel Jacek Kisielewicz Lothar Wiese Marie Helleberg Ole Kirk Michael R. Clausen Henrik Frederiksen 《European journal of haematology》2021,106(1):72-81
105.
106.
107.
108.
Rian M. Hasson Kayla A. Fay Joseph D. Phillips Timothy M. Millington David J. Finley 《American journal of surgery》2021,221(4):725-730
BackgroundRural populations face many health disadvantages compared to urban areas. There is a critical need to better understand the current lung cancer screening landscape in these communities to identify targeted areas to improve the impact of this proven tool.MethodsData from the County Health Rankings of New Hampshire and Vermont was reviewed for population density, distribution of adult smokers, and level of education compared to the distribution of Lung Cancer Screening Facilities throughout these two states.ResultsScreening programs in southern counties of Vermont with lower levels of education have decreased access. In New Hampshire, there are no programs within 30 miles of the areas with the largest distribution of smokers, and decreased access in some areas with the lowest levels of education.ConclusionsImproving equitable access to high-quality screening services in rural regions and the creation of targeted interventions to address decreased access in areas of high tobacco use and low education is vital to decreasing the incidence of latestage presentations of lung cancer within these populations. 相似文献
109.
IntroductionRealignment knee osteotomy relies on accurate preoperative assessment of coronal alignment. Weightbearing (WB) ‘long-leg’ (LL) radiographs are the accepted gold-standard investigation, though in practice standard knee radiographs (short leg; SL) and non-weightbearing (NWB) cross-sectional imaging such as computed tomography (CT) scanograms have been used. We compare the accuracy of SL and NWB radiographs to formal LL alignment radiographs.MethodsA prospectively maintained osteotomy database was reviewed to identify the study population. All patients underwent standardised weightbearing long-leg alignment radiographs. The series was screened consecutively until 30 patients who also underwent WB SL radiographs (‘WB cohort’), and 30 with NWB SL (‘NWB cohort’) radiographs, were identified. Anatomic tibiofemoral angle was calculated by independent reviewers using a validated technique from both radiographs and contrasted.Results60 patients were identified as outlined in the study protocol. There were no differences in baseline demographics. Coronal alignment calculated from SL and LL radiographs differed significantly (median difference 2.1°, p < 0.001). Alignment values from weightbearing SL radiographs demonstrated markedly greater agreement with LL values than those from NWB radiographs (intraclass correlation coefficient 0.878 vs 0.657), with the NWB cohort also exhibiting greater outlier and extreme outlier incidence.ConclusionOur data adds to the growing evidence that SL radiographs are inadequate in the interpretation of knee alignment. In addition, we demonstrate that NWB radiographs (and by extension other NWB modalities such CT scanograms) demonstrate poorer agreement to gold-standard than WB methods. Coronal alignment of the knee cannot be reliably measured from non-weightbearing imaging modalities.Implications for practiceThough potentially useful as an adjunct, non-weightbearing cross-sectional imaging and standard knee radiographs should not be used as a proxy for formal weightbearing long-leg radiographs in osteotomy planning. 相似文献
110.
Erik de Bakker Mirthe A. M. van der Putten Martijn W. Heymans Sander W. Spiekstra Taco Waaijman Liselotte Butzelaar Vera L. Negenborn Vivian K. Beekman Erman O. Akpinar Thomas Rustemeyer Frank B. Niessen Susan Gibbs 《Experimental dermatology》2021,30(1):169-178
Unpredictable hypertrophic scarring (HS) occurs after approximately 35% of all surgical procedures and causes significant physical and psychological complaints. Parallel to the need to understanding the mechanisms underlying HS formation, a prognostic tool is needed. The objective was to determine whether (systemic) immunological differences exist between patients who develop HS and those who develop normotrophic scars (NS) and to assess whether those differences can be used to identify patients prone to developing HS. A prospective cohort study with NS and HS groups in which (a) cytokine release by peripheral blood mononuclear cells (PBMC) and (b) the irritation threshold (IT) after an irritant (sodium lauryl sulphate) patch test was evaluated. Univariate regression analysis of PBMC cytokine secretion showed that low MCP‐1, IL‐8, IL‐18 and IL‐23 levels have a strong correlation with HS (P < .010‐0.004; AUC = 0.790‐0.883). Notably, combinations of two or three cytokines (TNF‐a, MCP‐1 and IL‐23; AUC: 0.942, Nagelkerke R2: 0.727) showed an improved AUC indicating a better correlation with HS than single cytokine analysis. These combination models produce good prognostic results over a broad probability range (sensitivity: 93.8%, specificity 86.7%, accuracy 90,25% between probability 0.3 and 0.7). Furthermore, the HS group had a lower IT than the NS group and an accuracy of 68%. In conclusion, very fundamental immunological differences exist between individuals who develop HS and those who do not, whereas the cytokine assay forms the basis of a predictive prognostic test for HS formation, the less invasive, easily performed irritant skin patch test is more accessible for daily practice. 相似文献